Our group researches molecular regulatory processes in microorganisms influenced by internal factors like small RNA molecules, the circadian clock, and supercoiling of DNA. Learning from the plethora of regulatory mechanisms, we design and test e.g. synthetic RNA switches, heterologous metabolic pathways, and biosensors. By implementing these parts and devices into microorganisms, we are aiming at a smart, automated, and dynamic control of signaling and metabolic pathways. Particular focus is placed on the engineering of Cyanobacteria as future hosts for a sustainable biotechnology.
© HHU / Ivo Mayr